1 - امور متعلقة بالرقود وعدم الحركة لمدة طويلة من الوقت كما قد يحدث فى بعض حالات الاعاقات والشلل و الكسور المضاعفة التى تحتاج لمدة طويلة من الوقت كى يلتحم الكسر.
2 - امور متعلقة بحدوث تضرر للأوردة. وهذا غير متحقق فى حال اصحاب الكهف.
3 - امور متعلقة بخلل وراثى يؤدى الى زيادة فى تجلط الدم. وهذا غير متحقق ايضا فى حال اصحاب الكهف.لان القران ذكر انهم لبثوا تلك المدة جميعا ونحن هنا لنبين كيف لبثوا تلك المدة ,لان اعتراض من يعترض بزعم عدم وجود كيفية تبرهن هذا اللبث تلك المدة و لهذا يزعم نفيها مع انها فى الاول و الاخر من ايات الله التى يحق لكل من انعم الله عز وجل عليه بالايمان ان يسلم لها اذا ذكرها ربنا فى كتابه المجيد.
e-medicine: Risk factors of deep venous thrombosis:
Many factors have been identified as known risk factors for the development of venous thrombosis. The single most powerful risk marker remains a prior history of DVT with up to 25% of acute venous thrombosis occurring in such patients.13 (**********:show*******('active','references');) Pathologically, remnants of previous thrombi are often seen within the specimens of new acute thrombi. However, recurrent thrombosis may actually be the result of primary hypercoagulable states. Abnormalities within the coagulation cascade are the direct result of discrete genetic mutations within the coagulation cascade. Deficiencies of protein C, protein S, or antithrombin III account for approximately 5-10% of all cases of deep venous thrombosis (DVT).14 (**********:show*******('active','references');)
Age has been well studied as an independent risk factor for venous thrombosis development. Although a 30-fold increase in incidence is noted from age 30 to age 80, the effect appears to be multifactorial, with more thrombogenic risk factors occurring in the elderly than in those younger than 40 years.13 (**********:show*******('active','references');),1 5 (**********:show*******('active','references');) Venous stasis, as seen in immobilized patients and paralyzed limbs, also contributes to the development of venous thrombosis. Autopsy studies parallel the duration of bed rest to the incidence of venous thrombosis, with 15% of patients in those studies dying within 7 days of bedrest to greater than 80% in those dying after 12 weeks.2 (**********:show*******('active','references');) Within stroke patients, deep venous thrombosis (DVT) is found in 53% of paralyzed limbs, compared with only 7% on the nonaffected side.16 (**********:show*******('active','references');)
Malignancy is noted in up to 30% of patients with venous thrombosis.13 (**********:show*******('active','references');),1 7 (**********:show*******('active','references');) The thrombogenic mechanisms involve abnormal coagulation, as evidenced by 90% of cancer patients having some abnormal coagulation factors.18 (**********:show*******('active','references');) Chemotherapy may increase the risk of venous thrombosis by affecting the vascular endothelium, coagulation cascades, and tumor cell lysis. The incidence has been shown to increase in those patients undergoing longer courses of therapy for breast cancer, from 4.9% for 12 weeks of treatment to 8.8% for 36 weeks.19 (**********:show*******('active','references');) Additionally, deep venous thrombosis (DVT) complicates 29% of surgical procedures done for malignancy.20 (**********:show*******('active','references');)
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